We have solved the crystal structure of the Holliday junction resolving enzyme T7 endonuclease I at 2.1 Å resolution using the multiwavelength anomalous dispersion (MAD) technique. Endonuclease I ...
RNA editing covalently alter the nucleotide sequence of RNA transcripts relative to that of the encoding DNA, thereby contributing to gene diversity 1. One of the most prevalent RNA modifications is ...
Regeneron is integrating single-use chromatographic clarification into its commercial-scale process for manufacturing adeno-associated vectors (AAVs), which enables it to eliminate endonuclease in ...
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