G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs. These receptors regulate a wide ...
Humans have bitter taste receptors not only in their mouths but in their lungs, too. Researchers have exploited these receptors’ innate ability to dilate the airways to create a potent new drug that ...
The FDA is weighing the regulatory fate of KarXT — an oral dual M1/M4 muscarinic acetylcholine receptor (mAChR) agonist — for schizophrenia. If approved, the fixed-dose combination of xanomeline and ...
G protein-coupled receptors (GPCRs) represent the largest family of membrane proteins and one of the most successful therapeutic targets in modern medicine, with approximately 34% of FDA-approved ...
Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis. But most patients with advanced disease eventually ...
A bitter taste receptor, TAS2R14, has been shown to respond to both extracellular and intracellular signals. Indeed, it can respond to both signals simultaneously. This finding is especially ...
DUBLIN--(BUSINESS WIRE)--The "Retinoic acid receptor agonists - Pipeline Insight, 2022" drug pipelines has been added to ResearchAndMarkets.com's offering. The report serves as an exhaustive source of ...
The upcoming drugs CagriSema and retatrutide target multiple gut hormones and could cause twice as much weight loss than ...
An existing drug currently used to treat glaucoma, altitude sickness, and seizures may also have the potential to prevent ...
Indiana University School of Medicine scientists have identified a promising drug target for Alzheimer's disease. The team ...
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